mostly right on the biology.
— Parmita Mishra (@parmita) April 20, 2026
digestion breaks DNA down; the modified sequence doesn’t end up in your cells.
no GMO tomato is going to give you a tomato gene. (THERE IS a caveat I cover below)
actual concerns are different and most of them aren’t about your cells at all
(1/) https://t.co/eX9ncwYaBz pic.twitter.com/bBa2zqoQI1
Most of the stigma is honestly 1990s-era marketing by organic industry + general “playing god” anxiety.
— Parmita Mishra (@parmita) April 20, 2026
Amplified by the fact that early GMO rollout happened with very little public communication, so it felt imposed. pic.twitter.com/T2YZrJmvwv
ecology
— Parmita Mishra (@parmita) April 20, 2026
roundup-ready crops led to massive glyphosate use, which has real effects on soil microbiomes, pollinators, and runoff
Bt crops put selection pressure on insect populations. The risk isn’t “eating DNA” lol it’s what industrial agriculture does to ecosystems at scale. pic.twitter.com/k46d5KjH9Y
Allergen / protein transfer is rare but real!
— Parmita Mishra (@parmita) April 20, 2026
the gene that gets inserted produces a protein, and that protein can occasionally be allergenic.
starlink corn had this issue in 2000.
The PROTEIN is the risk vector, not the DNA. pic.twitter.com/w85LBxNlCC
It claims that plant miR168a from rice crossed the gut barrier in mice and regulated LDLRAP1 in liver.
— Parmita Mishra (@parmita) April 20, 2026
it got huge attention because if true, it meant dietary RNA is a bona fide signaling molecule between kingdoms.
The current consensus is roughly: some small RNA can survive digestion in detectable amounts, but whether it reaches concentrations that actually regulate anything in recipient tissues is unproven and likely rare. pic.twitter.com/NOliN82E58
— Parmita Mishra (@parmita) April 20, 2026
So here’s the honest edge case:
— Parmita Mishra (@parmita) April 20, 2026
some small dietary RNAs (especially in milk exosomes and plant exosome-like vesicles) do survive digestion in detectable amounts.
Real phenomenon but OVERHYPED implications.
Does not meaningfully change the GMO safety picture.
Google raised, for several rounds, without revenue. Yes, it had a popular product with a rapidly growing user base. But biotech is a different paradigm. The barrier to entry is gladly high.
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Instagram sold without any revenue. Exit.
Unimaginative VCs talk revenue.
PreciGenetics: The Technology That Lets Us Watch Life Think: How Photons, Cells, and AI May Help Us Cure Cancer and Rewrite Medicine https://t.co/Sg6cw9e1kN
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Find the right VCs and RAISE. To attract the best of the best talent.
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Scientists can be PAID to push whatever narrative. Example: tobacco.
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Corporate food has destroyed the gut biome of Americans. That explains the obesity epidemic.
Corporate media tells Americans they are fat because they are lazy.
A double whammy.
Basmati rice has been a victim to genetic modification and corporate capture of seed. The original Basmati rice used to smell so good. The smell is completely gone.
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Sikkim style organic farming. Solution. Sadhguru's save the soil campaign.
"roundup-ready crops led to massive glyphosate use, which has real effects on soil microbiomes, pollinators, and runoff Bt crops put selection pressure on insect populations. The risk isn’t “eating DNA” lol it’s what industrial agriculture does to ecosystems at scale."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Huge.
"Seed patenting means farmers can’t save seeds. handful of companies (Monsanto/Bayer, Corteva, Syngenta) control most of the global seed supply."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Huge problem. Unacceptable.
"the gene that gets inserted produces a protein, and that protein can occasionally be allergenic."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Legitimate concern. And cannot be decoupled.
"dietary miRNA transfer from small non-coding RNAs (~22 nt) from food that appear to survive digestion and show up in mammalian blood."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
This sounds like the microplastics problem.
"The current consensus is roughly: some small RNA can survive digestion in detectable amounts, but whether it reaches concentrations that actually regulate anything in recipient tissues is unproven and likely rare."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
Not very reassuring.
"Horizontal gene transfer from food to gut microbiome happens. Not to your cells, to your bacteria. This is a real but contained phenomenon."
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
This is a huge problem. Rings alarm bells. Gut bacteria make the gut the second brain.
.... after just having listed 5 legitimate concerns, starting with out-of-control corporate power. And gut biome modifications. .......... this is food we are talking about.
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
But to be fair: India's Green Revolution relied on modified crops.
PreciGenetics: Ready To Raise https://t.co/WEgOqEz94o
— Paramendra Kumar Bhagat (@paramendra) April 20, 2026
